Preheat the oven to 350°F (175°C) and grease a casserole dish.
In a bowl, mix the flour, onion powder, garlic powder, paprika, salt, and pepper.
Coat each chicken piece with the flour mixture, shaking off any excess. Place the chicken in the prepared casserole dish.
In a separate bowl, combine the heavy whipping cream and water. Pour the mixture around the chicken in the casserole dish.
Bake in the preheated oven for about 90 minutes, or until the chicken is cooked through and tender.
Serve the Amish Chicken hot, spooning the creamy sauce over the top.